Joseph Edelman
Perceptive Advisors
Value
5.6B
Stocks
115 Stocks (39 new)
Turnover
24.65%
CIK
1224962
Top Holdings
PRAX(10.51%) CELC(5.63%) RYTM(4.87%) ASND(4.12%) APGE(3.14%)
About Investor
Established investor leading Perceptive Advisors, with expertise in fundamental analysis and long-term value creation. Has built a strong track record by focusing on fundamental research and maintaining a consistent investment approach through various market environments.
Investor Philosophy
Specializes in fundamental analysis and long-term value creation through a disciplined investment approach. Emphasizes thorough research, risk management, and identifying opportunities across market cycles. Known for maintaining a consistent strategy while adapting to changing market conditions.
| Ticker | Put/Call | Company Name | Industry | Value | Shares | Weighting % | Share Change | Change in Share % | Market Cap |
|---|---|---|---|---|---|---|---|---|---|
| PRAX | - | PRAXIS PRECISION MEDICINES I | Health Care | 588.30M | 1,995,986 | 10.51% | 431,432 | 27.58% | 9,086M |
| CELC | - | CELCUITY INC | Health Care | 315.20M | 3,160,200 | 5.63% | 203,881 | 6.90% | 4,868M |
| RYTM | - | RHYTHM PHARMACEUTICALS INC | Health Care | 272.57M | 2,546,391 | 4.87% | 107,422 | 4.40% | 6,766M |
| ASND | - | ASCENDIS PHARMA A/S | Health Care | 230.60M | 1,081,421 | 4.12% | -7,080 | -0.65% | 13,897M |
| APGE | - | APOGEE THERAPEUTICS INC | Health Care | 175.92M | 2,330,651 | 3.14% | 978,662 | 72.39% | 4,777M |
| ROIV | - | ROIVANT SCIENCES LTD | Health Care | 173.28M | 7,985,461 | 3.10% | 617,000 | 8.37% | 19,707M |
| NUVL | - | NUVALENT INC | Health Care | 167.49M | 1,665,105 | 2.99% | 102,769 | 6.58% | 7,940M |
| TVTX | - | TRAVERE THERAPEUTICS INC | Health Care | 163.47M | 4,278,180 | 2.92% | 483,565 | 12.74% | 2,499M |
| XBI | Put | SPDR SERIES TRUST | Other | 134.12M | 1,100,000 | 2.40% | 1,100,000 | New Buy | 8,336M |
| EXAS | - | EXACT SCIENCES CORP | Health Care | 121.92M | 1,200,487 | 2.18% | 735,000 | 157.90% | 19,633M |
| PTGX | - | PROTAGONIST THERAPEUTICS INC | Health Care | 117.95M | 1,350,425 | 2.11% | 320,291 | 31.09% | 5,159M |
| INBX | - | INHIBRX BIOSCIENCES INC | Health Care | 114.76M | 1,452,707 | 2.05% | 125,000 | 9.41% | 1,182M |
| EWTX | - | EDGEWISE THERAPEUTICS | Health Care | 110.62M | 4,457,974 | 1.98% | 662,080 | 17.44% | 3,190M |
| IMTX | - | IMMATICS N.V | Health Care | 109.03M | 10,383,456 | 1.95% | 1,000,000 | 10.66% | 1,320M |
| SYRE | - | SPYRE THERAPEUTICS INC | Health Care | 100.55M | 3,069,225 | 1.80% | 1,839,780 | 149.64% | 2,831M |
| AMLX | - | AMYLYX PHARMACEUTICALS INC | Health Care | 100.08M | 8,284,882 | 1.79% | -667,483 | -7.46% | 1,544M |
| ACLX | - | ARCELLX INC | Health Care | 95.59M | 1,466,071 | 1.71% | -1,002,282 | -40.61% | 4,000M |
| VRDN | - | VIRIDIAN THERAPEUTICS INC | Health Care | 94.69M | 3,042,703 | 1.69% | 1,580,303 | 108.06% | 2,676M |
| BSX | - | BOSTON SCIENTIFIC CORP | Health Care | 93.35M | 979,000 | 1.67% | 669,000 | 215.81% | 112,851M |
| FOLD | - | AMICUS THERAPEUTICS INC | Health Care | 90.72M | 6,370,851 | 1.62% | 0 | - | 4,500M |
| ZYME | - | ZYMEWORKS INC | Health Care | 85.88M | 3,261,850 | 1.53% | 1,171,187 | 56.02% | 1,742M |
| ATXS | - | ASTRIA THERAPEUTICS INC | Health Care | 84.89M | 6,485,420 | 1.52% | 0 | - | 718M |
| MGTX | - | MEIRAGTX HLDGS PLC | Health Care | 82.09M | 10,326,103 | 1.47% | -2,300,000 | -18.22% | 602M |
| AORT | - | ARTIVION INC | Health Care | 78.55M | 1,722,290 | 1.40% | -297,710 | -14.74% | 1,793M |
| CNTA | - | CENTESSA PHARMACEUTICALS PLC | Health Care | 72.97M | 2,917,634 | 1.30% | -183,268 | -5.91% | 3,757M |
| DYN | - | DYNE THERAPEUTICS INC | Health Care | 68.05M | 3,478,944 | 1.22% | 2,938,500 | 543.72% | 2,537M |
| NRIX | - | NURIX THERAPEUTICS INC | Health Care | 67.45M | 3,555,877 | 1.21% | 2,139,728 | 151.09% | 1,583M |
| SLDB | - | SOLID BIOSCIENCES INC | Health Care | 66.74M | 11,833,539 | 1.19% | 0 | - | 453M |
| BLTE | - | BELITE BIO INC | Health Care | 66.26M | 414,239 | 1.18% | 364,451 | 732.01% | 6,598M |
| ABVX | - | ABIVAX SA | Health Care | 61.81M | 458,343 | 1.10% | 69,735 | 17.94% | 10,075M |
| IVVD | - | INVIVYD INC | Health Care | 53.81M | 21,785,166 | 0.96% | 21,785,166 | New Buy | 458M |
| ENGN | - | ENGENE HOLDINGS INC | Health Care | 53.00M | 5,869,076 | 0.95% | 3,771,840 | 179.85% | 674M |
| RGEN | - | REPLIGEN CORP | Health Care | 51.70M | 315,541 | 0.92% | 45,113 | 16.68% | 7,791M |
| IMVT | - | IMMUNOVANT INC | Health Care | 50.71M | 1,994,890 | 0.91% | 407,000 | 25.63% | 5,410M |
| ISRG | - | INTUITIVE SURGICAL INC | Health Care | 49.79M | 87,919 | 0.89% | 35,800 | 68.69% | 177,540M |
| SION | - | SIONNA THERAPEUTICS INC | Health Care | 48.51M | 1,179,098 | 0.87% | 0 | - | 1,684M |
| NBIX | - | NEUROCRINE BIOSCIENCES INC | Health Care | 46.95M | 331,050 | 0.84% | -119,000 | -26.44% | 12,841M |
| DHR | - | DANAHER CORPORATION | Health Care | 45.78M | 200,000 | 0.82% | 200,000 | New Buy | 147,375M |
| ORKA | - | ORUKA THERAPEUTICS INC | Health Care | 44.75M | 1,476,501 | 0.80% | 208,480 | 16.44% | 1,562M |
| CTMX | - | CYTOMX THERAPEUTICS INC | Health Care | 41.24M | 9,680,185 | 0.74% | 0 | - | 894M |
| OMDA | - | OMADA HEALTH INC | Health Care | 37.81M | 2,396,330 | 0.68% | 0 | - | 679M |
| CDTX | - | CIDARA THERAPEUTICS INC | Health Care | 36.48M | 165,131 | 0.65% | 165,131 | New Buy | 6,962M |
| IRON | - | DISC MEDICINE INC | Health Care | 35.79M | 450,743 | 0.64% | 450,743 | New Buy | 2,472M |
| DRUG | - | BRIGHT MINDS BIOSCIENCES INC | Health Care | 35.06M | 449,290 | 0.63% | 0 | - | 802M |
| PEN | - | PENUMBRA INC | Health Care | 34.36M | 110,529 | 0.61% | -110,018 | -49.88% | 13,387M |
| ANRO | - | ALTO NEUROSCIENCE INC | Health Care | 31.76M | 1,784,393 | 0.57% | 1,629,027 | 1,048.51% | 556M |
| CAI | - | CARIS LIFE SCIENCES INC | Health Care | 30.65M | 1,136,206 | 0.55% | 38,043 | 3.46% | 5,939M |
| JAZZ | - | JAZZ PHARMACEUTICALS PLC | Health Care | 28.90M | 170,000 | 0.52% | 170,000 | New Buy | 10,209M |
| PALI | - | PALISADE BIO INC | Health Care | 28.32M | 12,050,000 | 0.51% | 12,050,000 | New Buy | 252M |
| RAPT | - | RAPT THERAPEUTICS INC | Health Care | 27.97M | 825,890 | 0.50% | 642,000 | 349.12% | 1,675M |
| PVLA | - | PALVELLA THERAPEUTICS INC NE | Health Care | 27.87M | 266,287 | 0.50% | -128,806 | -32.60% | 947M |
| AXSM | - | AXSOME THERAPEUTICS INC | Health Care | 27.20M | 148,900 | 0.49% | 0 | - | 9,320M |
| AXGN | - | AXOGEN INC | Health Care | 25.66M | 784,140 | 0.46% | 784,140 | New Buy | 1,767M |
| XFOR | - | X4 PHARMACEUTICALS INC | Health Care | 25.26M | 6,314,452 | 0.45% | 6,314,452 | New Buy | 263M |
| BCRX | - | BIOCRYST PHARMACEUTICALS INC | Health Care | 24.67M | 3,162,529 | 0.44% | 3,162,529 | New Buy | 1,792M |
| NAUT | - | NAUTILUS BIOTECHNOLOGY INC | Health Care | 24.56M | 12,594,211 | 0.44% | 0 | - | 327M |
| KOD | - | KODIAK SCIENCES INC | Health Care | 23.74M | 848,900 | 0.42% | 214,323 | 33.77% | 1,465M |
| BIIB | - | BIOGEN INC | Health Care | 21.82M | 124,000 | 0.39% | 124,000 | New Buy | 28,473M |
| ALDX | - | ALDEYRA THERAPEUTICS INC | Health Care | 21.68M | 4,185,632 | 0.39% | -1,036,679 | -19.85% | 298M |
| OBIO | - | ORCHESTRA BIOMED HLDGS INC | Health Care | 21.28M | 5,127,256 | 0.38% | -165,300 | -3.12% | 226M |
| MIRM | - | MIRUM PHARMACEUTICALS INC | Health Care | 20.50M | 259,545 | 0.37% | 259,545 | New Buy | 6,265M |
| RAPP | - | RAPPORT THERAPEUTICS INC | Health Care | 20.45M | 673,923 | 0.37% | 270,000 | 66.84% | 1,387M |
| GRAL | - | GRAIL INC | Health Care | 20.31M | 237,342 | 0.36% | 237,342 | New Buy | 3,987M |
| IRTC | - | IRHYTHM TECHNOLOGIES INC | Health Care | 19.16M | 108,000 | 0.34% | -15,000 | -12.20% | 5,034M |
| BBNX | - | BETA BIONICS INC | Health Care | 18.37M | 602,944 | 0.33% | 325,000 | 116.93% | 599M |
| CVS | - | CVS HEALTH CORP | Health Care | 17.46M | 220,000 | 0.31% | 220,000 | New Buy | 98,864M |
| CTNM | - | CONTINEUM THERAPEUTICS INC | Health Care | 16.74M | 1,464,592 | 0.30% | 750,000 | 104.95% | 555M |
| GH | - | GUARDANT HEALTH INC | Health Care | 16.34M | 160,000 | 0.29% | 160,000 | New Buy | 13,974M |
| ADMA | - | ADMA BIOLOGICS INC | Health Care | 16.11M | 883,468 | 0.29% | -270,000 | -23.41% | 3,803M |
| RLAY | - | RELAY THERAPEUTICS INC | Health Care | 16.10M | 1,903,245 | 0.29% | 1,903,245 | New Buy | 1,574M |
| GKOS | - | GLAUKOS CORP | Health Care | 15.81M | 140,000 | 0.28% | 140,000 | New Buy | 6,907M |
| DXCM | - | DEXCOM INC | Health Care | 14.98M | 225,758 | 0.27% | 225,758 | New Buy | 28,202M |
| SVRA | - | SAVARA INC | Health Care | 14.47M | 2,400,000 | 0.26% | 2,400,000 | New Buy | 1,132M |
| LONA | - | ATHIRA PHARMA INC | Health Care | 14.08M | 1,859,322 | 0.25% | 1,319,026 | 244.13% | 44M |
| SEPN | - | SEPTERNA INC | Health Care | 12.08M | 433,160 | 0.22% | -108,290 | -20.00% | 1,268M |
| IKT | - | INHIBIKASE THERAPEUTICS INC | Health Care | 11.11M | 5,421,568 | 0.20% | 0 | - | 216M |
| ADGM | - | ADAGIO MED HLDGS INC | Health Care | 10.27M | 9,876,576 | 0.18% | 0 | - | 21M |
| OCS | - | OCULIS HOLDING AG | Health Care | 9.86M | 493,827 | 0.18% | 493,827 | New Buy | 1,657M |
| GOSS | - | GOSSAMER BIO INC | Health Care | 9.73M | 3,139,669 | 0.17% | -673,128 | -17.65% | 491M |
| MPLT | - | MAPLIGHT THERAPEUTICS INC | Health Care | 9.66M | 550,000 | 0.17% | 550,000 | New Buy | 785M |
| XENE | - | XENON PHARMACEUTICALS INC | Health Care | 9.00M | 200,791 | 0.16% | 0 | - | 3,287M |
| IRD | - | OPUS GENETICS INC | Health Care | 8.69M | 4,325,000 | 0.16% | 0 | - | 258M |
| AVR | - | ANTERIS TECHNOLOGIES GLOBAL | Health Care | 8.36M | 1,675,476 | 0.15% | -29,654 | -1.74% | 550M |
| KMTS | - | KESTRA MED TECHNOLOGIES LTD | Health Care | 7.56M | 285,000 | 0.14% | 285,000 | New Buy | 1,491M |
| CAPR | Call | CAPRICOR THERAPEUTICS INC | Health Care | 6.99M | 242,100 | 0.12% | 242,100 | New Buy | 1,392M |
| BLLN | - | BILLIONTOONE INC | Health Care | 5.96M | 72,812 | 0.11% | 72,812 | New Buy | 4,102M |
| BHVN | Call | BIOHAVEN LTD | Health Care | 5.65M | 500,000 | 0.10% | 500,000 | New Buy | 1,525M |
| KYMR | - | KYMERA THERAPEUTICS INC | Health Care | 5.44M | 69,935 | 0.10% | -99,861 | -58.81% | 6,763M |
| PEPG | - | PEPGEN INC | Health Care | 5.40M | 829,870 | 0.10% | 0 | - | 445M |
| CBIO | - | CRESCENT BIOPHARMA INC. | Health Care | 5.38M | 453,686 | 0.10% | 0 | - | 296M |
| TENX | - | TENAX THERAPEUTICS INC | Health Care | 5.35M | 439,142 | 0.10% | 439,142 | New Buy | 77M |
| CRVS | - | CORVUS PHARMACEUTICALS INC | Health Care | 5.33M | 692,441 | 0.10% | -746,154 | -51.87% | 1,501M |
| TECX | Call | TECTONIC THERAPEUTIC INC | Health Care | 5.22M | 250,000 | 0.09% | 250,000 | New Buy | 400M |
| AQST | - | AQUESTIVE THERAPEUTICS INC | Health Care | 4.83M | 747,193 | 0.09% | -3,012,906 | -80.13% | 464M |
| TNGX | - | TANGO THERAPEUTICS INC | Health Care | 4.55M | 513,035 | 0.08% | 513,035 | New Buy | 1,659M |
| KRYS | - | KRYSTAL BIOTECH INC | Health Care | 4.31M | 17,500 | 0.08% | -17,500 | -50.00% | 8,319M |
| COGT | - | COGENT BIOSCIENCES INC | Health Care | 4.30M | 121,082 | 0.08% | 121,082 | New Buy | 5,803M |
| OLMA | - | OLEMA PHARMACEUTICALS INC | Health Care | 4.14M | 165,713 | 0.07% | 165,713 | New Buy | 1,802M |
| SDGR | - | SCHRODINGER INC | Health Care | 3.62M | 202,400 | 0.06% | 202,400 | New Buy | 871M |
| OM | - | OUTSET MED INC | Health Care | 3.09M | 833,333 | 0.06% | 0 | - | 63M |
| SABS | - | SAB BIOTHERAPEUTICS INC | Health Care | 3.00M | 803,210 | 0.05% | 803,210 | New Buy | 179M |
| AVTX | - | AVALO THERAPEUTICS INC | Health Care | 2.54M | 139,667 | 0.05% | 0 | - | 278M |
| CNTB | - | CONNECT BIOPHARMA HLDGS LTD | Health Care | 2.24M | 792,696 | 0.04% | 792,696 | New Buy | 164M |
| IMMX | - | IMMIX BIOPHARMA INC | Health Care | 1.77M | 338,941 | 0.03% | 338,941 | New Buy | 411M |
| LXEO | - | LEXEO THERAPEUTICS INC | Health Care | 1.39M | 139,835 | 0.02% | 0 | - | 458M |
| CPIX | - | CUMBERLAND PHARMACEUTICALS I | Health Care | 1.36M | 341,087 | 0.02% | 341,087 | New Buy | 58M |
| MDLN | - | MEDLINE INC | Health Care | 1.18M | 28,000 | 0.02% | 28,000 | New Buy | 39,704M |
| PTN | - | PALATIN TECHNOLOGIES INC | Health Care | 1.08M | 70,000 | 0.02% | 70,000 | New Buy | 33M |
| LENZ | - | LENZ THERAPEUTICS INC | Health Care | 0.80M | 50,000 | 0.01% | 50,000 | New Buy | 395M |
| BDSX | - | BIODESIX | Health Care | 0.74M | 108,694 | 0.01% | 0 | - | 101M |
| NVNO | - | ENVVENO MEDICAL CORPORATION | Health Care | 0.56M | 1,759,035 | 0.01% | 0 | - | 6M |
| IOVA | - | IOVANCE BIOTHERAPEUTICS INC | Health Care | 0.42M | 152,714 | 0.01% | 152,714 | New Buy | 1,082M |
| RVMDW | - | REVOLUTION MEDICINES INC | Health Care | 0.23M | 250,000 | 0.00% | 0 | - | 19,291M |
| ENSC | - | ENSYSCE BIOSCIENCES INC | Health Care | 0.08M | 86,666 | 0.00% | 0 | - | 1M |
| SRZNW | - | SURROZEN INC | Health Care | 0.00M | 166,666 | 0.00% | 0 | - | 215M |
